Simon Twigger @ MCW

bioinformatics and related stuff

Archives for the ‘Publications’ Category

The Gene Ontology’s Reference Genome Project, PLoS Comp. Biol. July 2009

By Simon • Sep 14th, 2009 • Category: Bioinformatics, Publications

We are funded as part of the Gene Ontology consortium and participate in GO’s Reference Genome project with RGD’s work in this area being spearheaded by Stan Laulederkind. The consortium recently published a paper describing this project and its work annotating genes across a wide variety of species.
The Gene Ontology’s Reference Genome Project: a unified [...]



Low cost, scalable proteomics data analysis using Amazon’s cloud computing services and open source search algorithms. J. Proteome Res. June 2009

By Simon • Sep 14th, 2009 • Category: Proteomics, Publications

We have been doing some work using Amazon’s cloud computing infrastructure (EC2, S3) as a platform for compute-intensive analyses that would normally require the purchase of a local cluster. Tailored to proteomics analysis of mass spec data, this work was recently published in the Journal of Proteomics Research.
Low cost, scalable proteomics data analysis using Amazon’s [...]



RGD article in Nucleic Acids Research, Database Edition

By Simon • Jan 8th, 2009 • Category: News, Publications

RGD’s latest publication has just come out in the January edition of Nucleic Acids Research. Entitled ‘Variation, ontologies and pathways’ the article describes the new features introduced on the Rat Genome Database over the past year including pathway diagrams, updates to the Genome browser, new physiological portals and more.

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Big data: The future of biocuration - Nature, Sept. 2008

By Simon • Sep 4th, 2008 • Category: News, Publications

As part of Nature’s general feature on the challenges of dealing with Big Data in modern scientific research there was an article published covering Biocuration and its associated challenges. Coming in part from the various Biocurator and International Biocurator meetings originally started from a grant awarded to Sue Rhee and Simon Twigger, this paper outlines [...]